Article

2021-09-27 Science & Technology

Antihistamines and azithromycin as a treatment for COVID-19 on primary health care – A retrospective observational study in elderly patients

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Posted by Thing From Snowy Mountain 2021-09-27 00:00|| E-Mail|| Front Page|| [11129 views ] Top

#1 I need to look up more on the dosages used here and about dexchlorpheniramine. My vision is lousy atm, I'll check in the morning.

Posted by Thing From Snowy Mountain 2021-09-27 00:23|| 2021-09-27 00:23|| Front Page Top

#2 Yes indeed. First line of attack. Nip it in the bud. When you have a severe ankle sprain with edema, its the edema that slows healing. Clear inflammation. Increase circulation. Then I increase warmth. I have found you need four things to manage most if not all major illnesses. Most major illnesses if not all thrive on low oxygen levels, normal body temperature, acidic chemistry and poor circulation.

Posted by Dale 2021-09-27 03:46|| 2021-09-27 03:46|| Front Page Top

#3 If she ever gets down to a normal weight, those tats of hers'll look like used cond0ms

Posted by Faux Drapeau 2021-09-27 04:10|| 2021-09-27 04:10|| Front Page Top

#4 When the buzz first started about HOCQ, it was being served up with a dose of Azithromycin. The word then that adverse effects were related to Azithromycin not HOCQ. I'd do more research at least before any treatments with Azithromycin.

Posted by Mercutio 2021-09-27 08:44|| 2021-09-27 08:44|| Front Page Top

#5 Lancet hit piece in 5, 4, 3 ....

Posted by Angstrom 2021-09-27 10:17|| 2021-09-27 10:17|| Front Page Top

#6 Mercutio, as I keep pointing out, the studies with the adverse effects from HCQ were a) done with HCQ alone and b) done with intentional overdoses on patients with compromised kidney function. It wasn't due to the azithromycin.

Posted by Thing From Snowy Mountain 2021-09-27 11:06|| 2021-09-27 11:06|| Front Page Top

#7 But that's a distraction. I said last night I'd look up dosage information when my eyes started focusing again.

Fred, according to the box here, 10 mg per 24 hours is a standard dose; this study was using 20 mg per 24 hour period, plus 2 mg dexchlorpheniramine every 12 hour. My next step is going to be looking up dexchlorpheniramine more thoroughly.

Posted by Thing From Snowy Mountain 2021-09-27 11:08|| 2021-09-27 11:08|| Front Page Top

#8 Another addition to my morning supplement regimen.

Posted by Skidmark 2021-09-27 12:14|| 2021-09-27 12:14|| Front Page Top

#9 dex...etc does not appear to be an over-the-counter drug in the US. I talked to one pharmacist who said she believed that the stuff in chlortrimeton was a close isomer, but I'll be double-checking that later.

Posted by Thing From Snowy Mountain 2021-09-27 12:34|| 2021-09-27 12:34|| Front Page Top

#10 Snowy. The point I was trying to make is that azithromycin alone has been found to have adverse side effects and, yes, some of the original HOCQ treatments were given along with Azithromycin which is where some of the anti-HOCQ press came from.

Posted by Mercutio 2021-09-27 18:28|| 2021-09-27 18:28|| Front Page Top

#11 Mercutio: You're either not listening or not reading for comprehention.

There were multiple fraudulent studies that "proved" that "HCQ alone" did not work.

The big one was the Surgisphere study that had completely fabricated data, was published in The Lancet, and retracted.

Posted by Thing From Snowy Mountain 2021-09-27 19:23|| 2021-09-27 19:23|| Front Page Top

#12 (to be continued)

Posted by Thing From Snowy Mountain 2021-09-27 19:24|| 2021-09-27 19:24|| Front Page Top

#13 When that was discovered they also created a second wave of studies, where patients were administered unsafe doses of HCQ with the objective of "proving" it didn't work.

Here's a link with more details: How a False Hydroxychloroquine Narrative Was Created
June 28, 2020.

There are a lot of links you can follow there, including in particular this one: WHO and UK trials use potentially lethal hydroxychloroquine dose--according to WHO consultant.

Posted by Thing From Snowy Mountain 2021-09-27 19:25|| 2021-09-27 19:25|| Front Page Top

#14 Now one thing I've found that's interesting that AFAIK hasn't been followed up on: Surgisphere did a similar data-fabricated-from-whole-cloth paper on... not an antimalarial, not a horse paste... but on a damn common human drug, one I take myself: ACE inhibitors.

Medpage Today: Retracted COVID Paper Lives on in New Citations:

Researchers around the world have continued breathing new life into a retracted study, which suggested that common antihypertensive medications were harmful in patients with COVID-19.

Published online on May 1, 2020 in the New England Journal of Medicine, the study relied on Surgisphere data to claim an association between renin-angiotensin-aldosterone system (RAAS) inhibitor therapy and worse outcomes in hospitalized COVID-19 patients with cardiovascular disease.

The journal retracted the paper due to concerns about fraudulent data on June 4, 2020 in a widely publicized move, but the study has continued to rack up citations -- totaling at least 652 as of May 31, 2021, reported Todd Lee, MD, MPH, of McGill University in Montreal, and colleagues.

According to my notes, it was further linked to from slashdot.

(I know, I was surprised to find out slashdot still exists).

Anyway, I'd like to see a link to the supposed study on azithromycin.

Posted by Thing From Snowy Mountain 2021-09-27 19:26|| 2021-09-27 19:26|| Front Page Top

#15 Sorry about the breakup into several different comments, the computer didn't like me today.

Posted by Thing From Snowy Mountain 2021-09-27 19:26|| 2021-09-27 19:26|| Front Page Top

#16 Both retracted Lancet studies relied on data provided by Dr. Sapan Desai, a known fraudster.

Posted by Angstrom 2021-09-27 20:58|| 2021-09-27 20:58|| Front Page Top

#17 Angstrom: If any one of the alleged 17 or so intelligence agencies the US had were an actual intelligence agency, there would have been followup questions about Dr. Desai and his company. And also more scrutiny and due diligence would have been done about papers matching his alleged findings.

Posted by Thing From Snowy Mountain 2021-09-27 22:22|| 2021-09-27 22:22|| Front Page Top

#18 Cain't we all jus' ....
rip each other's throats out?

Posted by Rexque Rodney Rexque Futuram 2021-09-27 23:40|| 2021-09-27 23:40|| Front Page Top

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