Direct Translation via Google Translate. Edited.
[Regnum] Scientists from the University of California at Los Angeles have identified a possible reason for the desire to eat even after satiety. As it became known on March 20, activation of special cells vgat PAG of the periaqueductal gray matter in the integument of the midbrain stimulates the body to search for food even if it is already full. The results of the study were published by Nature Communications (Nat Com).
During experiments on laboratory mice, it turned out that the search for additional food upon reaching satiety is due to the activity of vgat PAG, which increases in fear and anxiety. Artificial stimulation of these cells confirmed that the conclusions were correct: when exposed to light, the cells became active and caused anxiety in well-fed rodents, which is why they began to actively monitor moving objects and rush in pursuit of live crickets.
It turned out that humans have a similar mechanism. Their vgat PAG cells are located in the brain stem. According to researchers, their activation or constant hyperactivity can lead to the abuse of fatty and sweet foods even when the body is full.
As Regnum reported, in November 2023, scientists from the University of Sydney found that a lack of protein in a person’s diet can lead to excess weight gain. Its unbalanced intake into the body is one of the main causes of obesity in the world. When consuming high-carbohydrate, high-fat foods, a person may still feel hungry due to lack of protein, and diluting it in a diet high in fat and carbohydrates, resulting in increased energy consumption, is called “protein leverage.”
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