Matt Holman, chief of the office of science in the agency's Center for Tobacco Products (CTP), announced his departure from the FDA on Tuesday, effective immediately, after having served at the agency for more than 20 years.
His departure adds to ongoing trouble within the FDA's tobacco control division, which is currently under review by agency commissioner Robert Califf.
It also follows the division's loss of Mitch Zeller, who retired in April after serving as CTP director for nearly a decade. Brian King, who announced Holman's resignation in an internal memo, was appointed director earlier this month.